Methysticin
Methysticin is a kavalactone isolated from the kava roots. Methylsticin exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neurons and astroglia, decreases peak amplitude of voltage-gated Na+ channels in hippocampal neurons, and suppresses growth of Fusarium, Trichoderma, and Colletotrichum.The kavalactones, and compositions thereof, are useful in mediating osteoclast activity, and as such, are useful in treating or preventing disease or disease symptoms mediated by osteoclast activity.
Product Specifications
CAS Number
495-85-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 25 mg/mL (91.15 mM)
Smiles
O=C1C=C (OC) C[C@H] (/C=C/C2=CC=C (OCO3) C3=C2) O1
Molecular Formula
C15H14O5
Molecular Weight
274.27
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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