Biotin-PEG3-acid
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Product Specifications
CAS Number
252881-76-8
Field of Research
Cell Biology
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (223.44 mM)
Smiles
O=C1N[C@]2 (CS[C@H] ([C@]2 (N1) [H]) CCCCC (NCCOCCOCCOCCC (O) =O) =O) [H]
Molecular Formula
C19H33N3O7S
Molecular Weight
447.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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