DSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Product Specifications
CAS Number
68528-80-3
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (678.72 mM)
Smiles
O=C (ON1C (CCC1=O) =O) CCCCCCC (ON2C (CCC2=O) =O) =O
Molecular Formula
C16H20N2O8
Molecular Weight
368.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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