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Poly (I:C)

Poly (I:C) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts as the most potent interferon (IFN) inducer. It also is a Toll-like receptor- 3 (TLR3) agonist.Mixtures that included the TLR7/8 agonists R848 or CL075, combined with the poly (I:C) can produce 3-d mature dendritic cells .

Product Specifications

CAS Number

24939-03-5

Purity

90%

Solubility

H2O:21.5mg/mL; DMSO:<1 mg/mL

Smiles

O[C@@H] ([C@H] (N1C (NC=NC2=O) =C2N=C1) O[C@@H]3COP (O) (O) =O) [C@@H]3O.O[C@H] ([C@@H] (COP (O) (O) =O) O[C@H]4N5C=CC (N) =NC5=O) [C@@H]4O

Molecular Formula

C19H27N7O16P2

Molecular Weight

671.41

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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