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SCH 442416

SCH-442416 is an selective antagonist of adenosine A2A receptor. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively) .The A2A receptor antagonist (SCH 442416) could increase mRNA expression of the Kir 2.1and Kir 4.1 channels in Müller cells to protect the retinal neurons in vitro under hypoxic conditions.

Product Specifications

CAS Number

316173-57-6

Field of Research

Signal Transduction

Purity

>98% (HPLC)

Solubility

DMSO:Soluble

Smiles

COc1ccc (cc1) CCCn2c3c (cn2) c4nc (nn4c (n3) N) c5ccco5

Molecular Formula

C20H19N7O2

Molecular Weight

389.42

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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