SCH 442416
SCH-442416 is an selective antagonist of adenosine A2A receptor. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively) .The A2A receptor antagonist (SCH 442416) could increase mRNA expression of the Kir 2.1and Kir 4.1 channels in Müller cells to protect the retinal neurons in vitro under hypoxic conditions.
Product Specifications
CAS Number
316173-57-6
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO:Soluble
Smiles
COc1ccc (cc1) CCCn2c3c (cn2) c4nc (nn4c (n3) N) c5ccco5
Molecular Formula
C20H19N7O2
Molecular Weight
389.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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