What is the catalog number for AZ7550?

The catalog number for AZ7550 is orb1219220.

What sizes are available for AZ7550?

AZ7550 is available in the following size(s): 200 mg, 500 mg, 1 g, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does AZ7550 come in?

AZ7550 is available in 8 different pack sizes.

AZ7550 is currently made to order / not held in immediate stock. Contact us for lead time.

AZ7550

AZ7550 (Compound 28) appeares to offer a broadly similar potency and selectivity profile to the parent compound AZD9291. AZ7550 inhibits double mutant (DM) cell line H1975, activating mutant (AM) cell line PC9, and wild type (WT) cell line LoVo with IC50s of 45, 26, and 786 nM, respectively. AZ7550 inhibits DM antiproliferative cell line H1975, AM antiproliferative cell line PC9, and WT antiproliferative cell line Calu3 with GI50s of 19, 15, and 537 nM, respectively.

Product Specifications

CAS Number

1421373-99-0

Purity

>98% (HPLC)

Solubility

Soluble in DMSO

Smiles

CNCCN (C) c1cc (OC) c (Nc2nccc (n2) c3cn (C) c4ccccc34) cc1NC (=O) C=C

Molecular Formula

C??H??N?O?

Molecular Weight

485.58

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Propenamide, N- (4-methoxy-5- ((4- (1-methyl-1H-indol-3-yl) -2-pyrimidinyl) amino) -2- (methyl (2- (methylamino) ethyl) amino) phenyl) - InChi Key: ZROCWKZRGJYPTG-UHFFFAOYSA-N