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Zamicastat

Zamicastat is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP (IC50 values of 73.8 μM and 17.0 μM, respectively) .

Product Specifications

CAS Number

1080028-80-3

Product Name Alternative

BIA 5-1058

Purity

>98% (HPLC)

Solubility

DMSO:150 mg/mL (373.63 mM; Need ultrasonic)

Smiles

Fc (cc1F) cc (C2) c1OC[C@@H]2N (C (CCNCc1ccccc1) =CN1) C1=S

Molecular Formula

C21H21F2N3OS

Molecular Weight

401.47

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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