BI-671800
BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) . With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.
Product Specifications
CAS Number
1093108-50-9
Product Name Alternative
AP-761 | Cmpd A
Purity
>98% (HPLC)
Solubility
DMSO:130 mg/mL (259.22 mM; Need ultrasonic)
Smiles
CN (C) c1nc (Cc (cc2) ccc2NC (c2ccc (C (F) (F) F) cc2) =O) nc (N (C) C) c1CC (O) =O
Molecular Formula
C25H26F3N5O3
Molecular Weight
501.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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