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BI-671800

BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) . With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.

Product Specifications

CAS Number

1093108-50-9

Product Name Alternative

AP-761 | Cmpd A

Purity

>98% (HPLC)

Solubility

DMSO:130 mg/mL (259.22 mM; Need ultrasonic)

Smiles

CN (C) c1nc (Cc (cc2) ccc2NC (c2ccc (C (F) (F) F) cc2) =O) nc (N (C) C) c1CC (O) =O

Molecular Formula

C25H26F3N5O3

Molecular Weight

501.5

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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