IAXO-102
IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development.
Product Specifications
CAS Number
1115270-63-7
Purity
>98% (HPLC)
Solubility
Ethanol:45 mg/mL (76.8 mM; Need ultrasonic) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCCCCCCCCCCCCCO[C@@H] ([C@@H] ([C@@H] (CN) O[C@@H]1OC) O) [C@H]1OCCCCCCCCCCCCCC
Molecular Formula
C35H71NO5
Molecular Weight
585.94
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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