SCH-37370
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM) .
Product Specifications
CAS Number
117796-52-8
Product Name Alternative
SCH 37370 | SCH37370
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO:Soluble
Smiles
CC (N (CC1) CCC1=C (c (cc1) c (CC2) cc1Cl) c1c2cccn1) =O
Molecular Formula
C21H21ClN2O
Molecular Weight
352.86
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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