CDDO-dhTFEA
CDDO-dhTFEA is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. It restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats.
Product Specifications
CAS Number
1191265-33-4
Product Name Alternative
RTA dh404
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (174.00 mM; Need ultrasonic)
Smiles
C[C@@]12CC[C@@H]3[C@@] ([C@H]1CC (=O) [C@H]4[C@]2 (CC[C@@]5 ([C@H]4CC (CC5) (C) C) C (=O) NCC (F) (F) F) C) (C=C (C (=O) C3 (C) C) C#N) C
Molecular Formula
C33H45F3N2O3
Molecular Weight
574.72
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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