Meropenem trihydrate
Meropenem trihydrate with broad-spectrum antibacterial activity, is a carbapenem antibiotic. (In Vitro) :Meropenem is intrinsically stable to dehydropeptidase-1 (DHP-1) degradation and Meropenem acts by inhibiting bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs) . Meropenem possesses broad-spectrum in vitro activity, which includes activity against many Gram-positive, Gram-negative and anaerobic bacteria; Meropenem lacks activity against Enterococcus faecium, methicillin-resistant Staphylococcus aureus and Stenotrophomonas maltophilia. (In Vivo) :Meropenem (60 mg/kg; intraperitoneal injection; once; SD rats) treatment significantly reduces the incidence of pancreatic infection.
Product Specifications
CAS Number
119478-56-7
Product Name Alternative
SM 7338 trihydrate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:90 mg/mL (205.71 mM; Need ultrasonic) ; H2O:12 mg/mL (27.43 mM; Need ultrasonic)
Smiles
O=C (C (N12) =C (S[C@@H]3CN[C@H] (C (N (C) C) =O) C3) [C@H] (C) [C@]2 ([H]) [C@@H] ([C@H] (O) C) C1=O) O.[H]O[H].[H]O[H].[H]O[H]
Molecular Formula
C17H31N3O8S
Molecular Weight
437.51
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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