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NF-κB-IN-1

NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.

Product Specifications

CAS Number

1227098-15-8

Product Name Alternative

1,6-Heptadiene-3,5-dione, 1,7-bis (3,4-dimethoxyphenyl) -4-[ (4-hydroxy-3-methoxyphenyl) methylene]-, (1E,6E) -

Purity

>98% (HPLC)

Solubility

DMSO:50 mg/mL (94.24 mM; Need ultrasonic)

Smiles

O=C (/C=C/C (C=C1) =CC (OC) =C1OC) /C (C (/C=C/C (C=C2) =CC (OC) =C2OC) =O) =C/C (C=C3) =CC (OC) =C3O

Molecular Formula

C31H30O8

Molecular Weight

530.57

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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