Rhosin hydrochloride
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM) . Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride causes cell apoptosis.
Product Specifications
CAS Number
1281870-42-5
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (253.25 mM; Need ultrasonic)
Smiles
O=C (N/N=C/C1=CC=C2N=CC=NC2=C1) [C@H] (N) CC3=CNC4=C3C=CC=C4.Cl
Molecular Formula
C20H19ClN6O
Molecular Weight
394.86
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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