Bisindolylmaleimide VIII acetate
Bisindolylmaleimide VIII acetate is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC) . It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.
Product Specifications
CAS Number
138516-31-1
Product Name Alternative
Ro 31-7549 acetate | Bis VIII acetate
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (545.24 mM)
Smiles
O=C (C (C1=CN (CCCN) C2=C1C=CC=C2) =C3C4=CN (C) C5=C4C=CC=C5) NC3=O.CC (O) =O
Molecular Formula
C26H26N4O4
Molecular Weight
458.51
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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