Isosilybin A
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.
Product Specifications
CAS Number
142796-21-2
Purity
>98% (HPLC)
Solubility
DMSO:90mg/ml (186.55mM; Need ultrasonic)
Smiles
COc (cc ([C@H]1Oc (ccc ([C@H] ([C@H] (C2=O) O) Oc3c2c (O) cc (O) c3) c2) c2O[C@@H]1CO) cc1) c1O
Molecular Formula
C25H22O10
Molecular Weight
482.44
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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