Lifirafenib
Lifirafenib is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.
Product Specifications
CAS Number
1446090-79-4
Product Name Alternative
Beigene-283 | BGB-283
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (209.02 mM)
Smiles
O=C1Nc2nccc (Oc (cc3) cc (C45) c3OC4C5c3nc (ccc (C (F) (F) F) c4) c4[nH]3) c2CC1
Molecular Formula
C25H17F3N4O3
Molecular Weight
478.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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