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Lifirafenib

Lifirafenib is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.

Product Specifications

CAS Number

1446090-79-4

Product Name Alternative

Beigene-283 | BGB-283

Purity

>98% (HPLC)

Solubility

DMSO:100 mg/mL (209.02 mM)

Smiles

O=C1Nc2nccc (Oc (cc3) cc (C45) c3OC4C5c3nc (ccc (C (F) (F) F) c4) c4[nH]3) c2CC1

Molecular Formula

C25H17F3N4O3

Molecular Weight

478.42

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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