PF-543 hydrochloride
PF-543 inhibits SphK1 with a K (i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Product Specifications
CAS Number
1706522-79-3
Purity
>98% (HPLC)
Solubility
DMSO:≥90 mg/mL (136.83mM)
Smiles
OC[C@@H]1N (CC2=CC=C (COC3=CC (CS (=O) (C4=CC=CC=C4) =O) =CC (C) =C3) C=C2) CCC1.[H]Cl
Molecular Formula
C27H32ClNO4S
Molecular Weight
502.1
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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