2,4-Diacetylphloroglucinol

2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings[1][2][3].

Product Specifications

CAS Number

[2161-86-6]

Product Name Alternative

BAL8557-002,(RS)-ECPG

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Antibiotic; Bacterial; Fungal; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-4-diacetylphloroglucinol.html

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C(C(O)=C(C(O)=C1)C(C)=O)C(C)=O

Molecular Formula

C10H10O5

Molecular Weight

210.18

Precautions

H302, H312, H332

References & Citations

[1]Susan L F Meyer, et al. Toxicity of 2,4-diacetylphloroglucinol (DAPG) to plant-parasitic and bacterial-feeding nematodes. J Nematol. 2009 Dec;41 (4) :274-80.|[2]Brazelton JN, et al. 2,4-diacetylphloroglucinol alters plant root development. Mol Plant Microbe Interact. 2008 Oct;21 (10) :1349-58.|[3]Islam MT, et al. 2,4-Diacetylphloroglucinol suppresses zoosporogenesis and impairs motility of Peronosporomycete zoospores. World J Microbiol Biotechnol. 2011 Sep;27 (9) :2071-2079.