KY19382
KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β (IC50s of 19 and 10 nM, respectively) . It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
Product Specifications
CAS Number
2226664-93-1
Product Name Alternative
2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3- (methoxyimino) -2H-indol-2-ylidene]-1,3-dihydro-Ky19382 | A3051
Purity
>98% (HPLC)
Solubility
DMSO:5 mg/mL (13.88 mM; Need ultrasonic)
Smiles
CO/N=C\1/C2=CC=CC=C2N=C1C3=C (NC4=CC (=C (C=C43) Cl) Cl) O
Molecular Formula
C17H11Cl2N3O2
Molecular Weight
360.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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