FGFR1/DDR2 inhibitor 1
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.
Product Specifications
CAS Number
2308497-58-5
Field of Research
Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:250 mg/mL (498.50 mM; Need ultrasonic) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
CC1=C (C=C (C=C1) C (=O) NC2=CC=CC (=C2) C (F) (F) F) C3=CC4=C (C=C3) C (=NN4) C5=CN (N=C5) C6CC6
Molecular Formula
C28H22F3N5O
Molecular Weight
501.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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