JHU 37160
JHU 37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
Product Specifications
CAS Number
2369979-68-8
Purity
>98% (HPLC)
Solubility
DMSO:72 mg/mL (200.65 mM) ; Ethanol:72 mg/mL (200.65 mM)
Smiles
FC1=C2NC3=CC=C (Cl) C=C3N=C (N4CCN (CC) CC4) C2=CC=C1
Molecular Formula
C19H20ClFN4
Molecular Weight
358.85
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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