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BI-2852

BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.

Product Specifications

CAS Number

2375482-51-0

Purity

>98% (HPLC)

Solubility

DMSO:55 mg/mL (106.47 mM; Need ultrasonic)

Smiles

Cn1cnc (Cn (cc2) c3c2ccc (CNCc2c ([C@H] (c4c5ccc (O) c4) NC5=O) c (cccc4) c4[nH]2) c3) c1

Molecular Formula

C31H28N6O2

Molecular Weight

516.59

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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