BI-2852
BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
Product Specifications
CAS Number
2375482-51-0
Purity
>98% (HPLC)
Solubility
DMSO:55 mg/mL (106.47 mM; Need ultrasonic)
Smiles
Cn1cnc (Cn (cc2) c3c2ccc (CNCc2c ([C@H] (c4c5ccc (O) c4) NC5=O) c (cccc4) c4[nH]2) c3) c1
Molecular Formula
C31H28N6O2
Molecular Weight
516.59
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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