BDTX-189
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations (KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively) . BDTX-189 exhibits anticancer activity.
Product Specifications
CAS Number
2414572-47-5
Purity
>98% (HPLC)
Solubility
DMSO:41.67 mg/mL (74.27 mM; Need ultrasonic)
Smiles
C=CC (=O) NC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) OCC4=CC=CC=N4) Cl) OCCN5CCOCC5
Molecular Formula
C29H29ClN6O4
Molecular Weight
561.03
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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