Solabegron
Solabegron is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR (EC50 : 22 nM) . It is used for treatment of overactive bladder and irritable bowel syndrome. (In Vivo) :Solabegron (GW427353) at 3 mg/kg i.v. evokes an increase in micturition volume threshold that prevented the acetic acid-evoked decreases in dogs. The low dose (1 mg/kg) shows no significant activity.
Product Specifications
CAS Number
252920-94-8
Product Name Alternative
GW 427353
Purity
>98% (HPLC)
Solubility
DMSO:250 mg/mL (608.44 mM; Need ultrasonic)
Smiles
C1=CC (=CC (=C1) C (=O) O) C2=CC (=CC=C2) NCCNC[C@@H] (C3=CC (=CC=C3) Cl) O
Molecular Formula
C23H23ClN2O3
Molecular Weight
410.89
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
303613 1 Pack (1 Panel (s) x 1 Pack)
P/P049/NL415/RFL-390X590-1 Prohibited Activity Signs & Labels (Adhesive)
Sign In for Pricing
View Details 
GTR15336576 1 Vial
Lentiviral human S100B shRNA (UAS) - Lentiviral human S100B shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details 038778-ML750 100 µL
NACC2, CT (NACC2, BTBD14A, NAC2, Nucleus accumbens-associated protein 2, BTB/POZ domain-containing protein 14A) (MaxLight 750) discontinued
Sign In for Pricing
View Details