Nimbolide
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L) .
Product Specifications
CAS Number
25990-37-8
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (107.18 mM)
Smiles
C[C@]12[C@@]3 ([H]) [C@] (OC ([C@@]3 (C=CC2=O) C) =O) ([H]) [C@]4 ([H]) [C@] ([C@@H]1CC (OC) =O) (C5=C (C) [C@@] (C6=COC=C6) ([H]) C[C@@]5 ([H]) O4) C
Molecular Formula
C27H30O7
Molecular Weight
466.52
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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