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Nimbolide

Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L) .

Product Specifications

CAS Number

25990-37-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (107.18 mM)

Smiles

C[C@]12[C@@]3 ([H]) [C@] (OC ([C@@]3 (C=CC2=O) C) =O) ([H]) [C@]4 ([H]) [C@] ([C@@H]1CC (OC) =O) (C5=C (C) [C@@] (C6=COC=C6) ([H]) C[C@@]5 ([H]) O4) C

Molecular Formula

C27H30O7

Molecular Weight

466.52

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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