Lanraplenib
Lanraplenib is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
Product Specifications
CAS Number
1800046-95-0
Product Name Alternative
GS-9876
Purity
>98% (HPLC)
Solubility
DMSO:41.67 mg/mL (93.96 mM; Need ultrasonic)
Smiles
C1CN (CCN1C2COC2) C3=CC=C (C=C3) NC4=NC (=CN5C4=NC=C5) C6=CN=CC (=N6) N
Molecular Formula
C23H25N9O
Molecular Weight
443.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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