KL1333
KL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD (P) H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.
Product Specifications
CAS Number
1800405-30-4
Product Name Alternative
NQO1 activator 1
Purity
>98% (HPLC)
Solubility
DMSO:245 mg/mL (1019.73 mM; Need ultrasonic)
Smiles
CC (C) c1nc (-c (cccc2) c2C (C2=O) =O) c2[nH]1
Molecular Formula
C14H12N2O2
Molecular Weight
240.26
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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