VU0650786
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.
Product Specifications
CAS Number
1809085-30-0
Purity
>98% (HPLC)
Solubility
DMSO: 240 mg/mL (618.88 mM; Need ultrasonic) ; H2O: insoluble
Smiles
ClC1=CN=C (OCC2=NN ([C@H] (C) CN (C3=C (F) N=CC=C3) C4=O) C4=C2) C=C1
Molecular Formula
C18H15ClFN5O2
Molecular Weight
387.8
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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