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TAK-981

TAK-981 is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities. (In Vitro) :Subasumstat (TAK-981) is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, activating innate effector cells and enhancing the antitumor innate immune responses. (In Vivo) :A single sub-cutaneous injection of Subasumstat (TAK-981) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs.

Product Specifications

CAS Number

1858276-04-6

Product Name Alternative

Subasumstat

Field of Research

Epigenetics & Chromatin

Purity

>98% (HPLC)

Solubility

DMSO:75 mg/mL (129.74 mM; Need ultrasonic)

Smiles

Cc1c ([C@@H]2NCCc (cc3) c2cc3Cl) cc (C (c2c (N[C@H] (C[C@@H]3COS (N) (=O) =O) C[C@@H]3O) ncnc2) =O) s1

Molecular Formula

C25H28ClN5O5S2

Molecular Weight

578.1

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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