Hinokiflavone
Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spliceosome assembly, specifically preventing B complex formation. Hinokiflavone is a SUMO protease inhibitor, inhibiting sentrin-specific protease 1 (SENP1) activity.Hinokiflavone has significant cytotoxicity, it has inhibition of MMP-9.
Product Specifications
CAS Number
19202-36-9
Purity
>98% (HPLC)
Solubility
DMSO:10 mM
Smiles
O=C1C=C (C2=CC=C (O) C=C2) OC3=CC (O) =C (OC4=CC=C (C5=CC (C6=C (O) C=C (O) C=C6O5) =O) C=C4) C (O) =C13
Molecular Formula
C30H18O10
Molecular Weight
538.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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