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Giredestrant

Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.

Product Specifications

CAS Number

1953133-47-5

Product Name Alternative

GDC-9545

Purity

>98% (HPLC)

Solubility

DMSO:100mg/mL (191.37 mM; Need ultrasonic)

Smiles

C[C@H] (Cc1c2[nH]c3c1cccc3) N (CC (CO) (F) F) [C@@H]2c (c (F) cc (NC1CN (CCCF) C1) c1) c1F

Molecular Formula

C27H31F5N4O

Molecular Weight

522.55

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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