Giredestrant
Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.
Product Specifications
CAS Number
1953133-47-5
Product Name Alternative
GDC-9545
Purity
>98% (HPLC)
Solubility
DMSO:100mg/mL (191.37 mM; Need ultrasonic)
Smiles
C[C@H] (Cc1c2[nH]c3c1cccc3) N (CC (CO) (F) F) [C@@H]2c (c (F) cc (NC1CN (CCCF) C1) c1) c1F
Molecular Formula
C27H31F5N4O
Molecular Weight
522.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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