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Epertinib hydrochloride

Epertinib hydrochloride shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.

Product Specifications

CAS Number

2071195-74-7

Product Name Alternative

S-22611 hydrochloride

Purity

>98% (HPLC)

Solubility

DMSO:125 mg/mL (209.56 mM; Need ultrasonic)

Smiles

CC#C/C (=N\OC[C@H]1COCCN1) /C2=CC3=C (C=C2) N=CN=C3NC4=CC (=C (C=C4) OCC5=CC (=CC=C5) F) Cl.Cl

Molecular Formula

C30H28Cl2FN5O3

Molecular Weight

596.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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