BPH-1358
BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL) .
Product Specifications
CAS Number
5352-53-4
Product Name Alternative
NSC50460
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 6.25 mg/mL (10.39 mM)
Smiles
O=C (C1=CC=C (C2=CC=C (C (NC3=CC=CC (C4=NCCN4) =C3) =O) C=C2) C=C1) NC5=CC=CC (C6=NCCN6) =C5.[H]Cl.[H]Cl
Molecular Formula
C32H30Cl2N6O2
Molecular Weight
601.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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