IHR-1
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM) . Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Product Specifications
CAS Number
548779-60-8
Purity
>98% (HPLC)
Solubility
DMSO:9.08 mg/mL
Smiles
C1=CC (=CC=C1NC (=O) C2=C (C=CC (=C2) Cl) Cl) NC (=O) C3=C (C=CC (=C3) Cl) Cl
Molecular Formula
C20H12Cl4N2O2
Molecular Weight
454.12
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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