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IHR-1

IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM) . Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.

Product Specifications

CAS Number

548779-60-8

Purity

>98% (HPLC)

Solubility

DMSO:9.08 mg/mL

Smiles

C1=CC (=CC=C1NC (=O) C2=C (C=CC (=C2) Cl) Cl) NC (=O) C3=C (C=CC (=C3) Cl) Cl

Molecular Formula

C20H12Cl4N2O2

Molecular Weight

454.12

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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