Pocapavir

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections[1].

Product Specifications

CAS Number

[146949-21-5]

Product Name Alternative

SCH-48973; V-073

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Enterovirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Pocapavir.html

Purity

99.59

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=C(OCC2=CC=C(COC3=CC=C(OC)C=C3Cl)C=C2)C(Cl)=CC=C1

Molecular Formula

C21H17Cl3O3

Molecular Weight

423.72

Precautions

H302, H315, H319

References & Citations

[1]Collett MS, et al. Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model. J Infect Dis. 2017 Feb 1;215 (3) :335-343.