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DNA2 inhibitor C5

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM) . DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.

Product Specifications

CAS Number

35973-25-2

Field of Research

Epigenetics & Chromatin; Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO:31.25 mg/mL (133.45 mM; Need ultrasonic)

Smiles

O=C (C1=C (O) C2=CC=CC ([N+] ([O-]) =O) =C2N=C1) O

Molecular Formula

C10H6N2O5

Molecular Weight

234.17

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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