Groenlandicine
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR) . Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage; Groenlandicine may be a promising anti-Alzheimer's disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO (-) scavenging and good ROS inhibitory capacities.
Product Specifications
CAS Number
38691-95-1
Purity
>98% (HPLC)
Solubility
DMSO:10 mM
Smiles
COC1=CC2=C (C=C1O) CC[N+]3=CC4=C (C=CC5=C4OCO5) C=C23
Molecular Formula
C19H16NO4
Molecular Weight
322.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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