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YUM70

YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor (with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein) . It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.

Product Specifications

CAS Number

423145-35-1

Purity

>98% (HPLC)

Solubility

DMSO:100 mg/mL (250.73 mM; Need ultrasonic)

Smiles

O=C (CCC) NC (C1=CC=C2C (OCO2) =C1) C (C=C (Cl) C3=C4N=CC=C3) =C4O

Molecular Formula

C21H19ClN2O4

Molecular Weight

398.84

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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