GN25
GN25 is a specific p53-Snail binding inhibitor with antitumor effects[1].
Product Specifications
CAS Number
[1227401-27-5]
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gn25.html
Concentration
10mM
Purity
98.55
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CCSC(C1=O)=CC(C2=C1C(OC)=CC=C2OC)=O
Molecular Formula
C15H14O6S
Molecular Weight
322.33
References & Citations
[1]Lee SH, Shen GN, Jung YS, Lee SJ, Chung JY, Kim HS, Xu Y, Choi Y, Lee JW, Ha NC, Song GY, Park BJ. Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells. Oncogene. 2010 Aug 12;29 (32) :4576-87.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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