(Rac) -LM11A-31
(Rac) -LM11A-31 is a racemate of LM11A-31. LM11A-31 is a non-peptide modulator of p75NTR (neurotrophin receptor p75) and is an orally effective proNGF antagonist[1].
Product Specifications
CAS Number
289475-77-0
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-lm11a-31.html
Smiles
CCC(C)C(N)C(=O)NCCN1CCOCC1
Molecular Formula
C12H25N3O2
Molecular Weight
243.35
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Elshaer SL, e al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62 (8) :1488-1500.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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