2-Iminobiotin hydrobromide
2-Iminobiotin hydrobromide is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS, respectively) . (In Vitro) :Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control.
Product Specifications
CAS Number
76985-52-9
Product Name Alternative
Guanidinobiotin | 2-IMINOBIOTIN HYDROBROMIDE
Purity
>98% (HPLC)
Solubility
DMSO:12.5 mg/mL (51.37 mM)
Smiles
[H][C@] (CS[C@H]1CCCCC (O) =O) ([C@]1 ([H]) N2) NC2=N.Br
Molecular Formula
C10H18BrN3O2S
Molecular Weight
324.24
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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