PID/MTA2 Polyclonal Antibody
Product Specifications
Storage Conditions
This antibody is stable for at least one (1) year at -20 °C. Avoid multiple freeze-thaw cycles.
Specificity
PID/MTA2 [This rabbit antibody recognizes aa 652-668 of human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. This antibody does not cross-react with MTA1.]<br>This antibody recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. This antibody does not cross-react with MTA1.
Short Name
[PID/MTA2]
CAS Number
9007-83-4
Available Sizes
Curated Selection
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