Prunasin
Prunasin is an orally active cyanogenic glucoside and the main metabolite of Amygdalin. Prunasin can specifically inhibit rat DNA polymerase β (IC50: 98 μM). Prunasin has anti-inflammatory and anti-fibrotic activities. Prunasin can be used in the research of diseases such as liver fibrosis[1][2].
Product Specifications
CAS Number
99-18-3
UNSPSC
12352005
Hazard Statement
H301, H360
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/prunasin.html
Purity
99.56
Solubility
H2O : ≥ 50 mg/mL
Smiles
N#C[C@@H](C1=CC=CC=C1)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
Molecular Formula
C14H17NO6
Molecular Weight
295.29
Precautions
H301, H360
References & Citations
[1]Mizushina Y, et al. The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta. J Biochem. 1999;126 (2) :430-436.|[2]Zhang C, et al. Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin. Phytomedicine. 2022 May;99:154018.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC227348L4 10 µg
KIAA0825 (NM_001145678) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 